Israel's military said it conducted air strikes targeting senior Hamas leaders in the Qatari capital on Tuesday, as Qatar condemned an attack on buildings housing members of the Palestinian militant movement.

Qatar, which has been a key mediator in efforts to broker a truce in Gaza, said Israeli strikes targeted the homes of several members of Hamas's political bureau residing in the Gulf country, where the militant group's senior leadership is based.

Israel's military said on Tuesday that it will act with "great force" in Gaza City and told residents to leave as it stepped up its deadly assault on the Palestinian territory's largest urban center.

Prime Minister Benjamin Netanyahu issued a similar warning, as Israel intensified its bombardment in preparation for an operation to seize Gaza City despite global calls to end the war.

Israeli air strikes hit areas of the central and western Syrian cities of Homs and Latakia late Monday, state news agency SANA reported.

Israel struck and destroyed another high-rise building in Gaza City on Monday after warning residents to evacuate, part of an offensive aimed at taking over the largest Palestinian city. The military said it was targeting Hamas observation posts and bombs placed around the 12-story office building.

Over the past several days, Israel has destroyed multiple high-rise buildings in Gaza City, accusing Hamas of putting surveillance infrastructure in them. It has ordered people to flee ahead of its ground offensive into the city of some 1 million residents, which experts say is experiencing famine.

Spanish Prime Minister Pedro Sánchez on Monday ratcheted up his criticism of Israel's actions in the 23-month Israel-Hamas war, to which Israel responded by banning two left-wing Spanish ministers from the country.

A drone fired by Yemen's Houthi rebels breached Israel's multilayered air defenses on Sunday and slammed into the country's southern airport, the Israeli military said, blowing out glass windows, wounding one person and briefly shutting down commercial airspace.

The damage to Ramon Airport appeared limited and flights resumed within hours. The Houthis claimed responsibility for the strike.

U.S. President Donald Trump said Sunday he was issuing a "last warning" to Hamas, saying the Palestinian militant group must accept a deal to release hostages in Gaza.

"The Israelis have accepted my terms. It is time for Hamas to accept as well. I have warned Hamas about the consequences of not accepting. This is my last warning," Trump said on social media, without elaborating further.

Israel's defense minister told Hamas on Monday to lay down its arms or face annihilation, after U.S. President Donald Trump said the militant group must accept a deal to release hostages in Gaza.

The warnings came as the Israeli military intensified its bombings and operations around Gaza City, which it has vowed to capture in a bid to finally defeat Hamas after nearly two years of devastating conflict.

Palestinian attackers opened fire at a bus stop during the morning rush hour in Jerusalem on Monday, killing six people and wounding another 12, according to Israeli officials.

The Israeli army said two projectiles were launched Sunday from the Gaza Strip, with Palestinian militant group Islamic Jihad claiming responsibility for the rocket fire, which caused no casualties or damage.