Israel's military said it was striking military targets in Tehran on Wednesday, as AFP journalists reported hearing blasts in the north and east of the Iranian capital.
The Israeli air force "is currently striking military targets belonging to the Iranian Regime in Tehran," the military said in a statement, on the sixth day of the war between the arch foes.
Israeli Defense Minister Israel Katz later said that air force jets had destroyed Iran's "internal security headquarters".
"Air Force jets have just destroyed the internal security headquarters of the Iranian regime -- the main arm of repression of the Iranian dictator," Katz said in a statement, vowing to "strike symbols of governance and hit the Ayatollah regime wherever it may be".
Earlier on Wednesday, Israel said it struck a nuclear site near Tehran , while Iran said it fired hypersonic missiles.
After the Israeli military issued a warning for civilians to leave one district of Tehran for their safety, Israeli warplanes hit the capital early Wednesday.
"More than 50 Israeli Air Force fighter jets... carried out a series of air strikes in the Tehran area over the past few hours," the Israeli military said, adding that several weapons manufacturing facilities were hit.
"As part of the broad effort to disrupt Iran's nuclear weapons development program, a centrifuge production facility in Tehran was targeted."
Centrifuges are vital for uranium enrichment, the sensitive process that can produce fuel for nuclear reactors or, in highly extended form, the core of a nuclear reactor.
Iran's Revolutionary Guards said they had launched hypersonic Fattah-1 missiles at Tel Aviv.
"The 11th wave of the proud Operation Honest Promise 3 using Fattah-1 missiles" was carried out, the Guards said in a statement broadcast on state television.
Hypersonic missiles travel at more than five times the speed of sound and can maneuver mid-flight, making them harder to track and intercept.
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